What is biotin dependence
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What Is Biotin Dependence
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What Is Biotin Dependence
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P values were calculated using Student's t-test;. DESCRIPTION Early-onset multiple carboxylase deficiency, or holocarboxylase deficiency, is an autosomal recessive disorder of biotin metabolism. Holocarboxylase synthetase (HCS) plays an essential role in biotin utilization in eukaryotic cells and its deficiency causes biotin-responsive multiple carboxylase deficiency in humans. Temperature dependence of individual biotin-avidin unbinding forces Fi. Biotin-responsive multiple carboxylase deficiency is an inherited disorder of organic acid metabolism in man in which there are deficiencies of propionyl-coenzyme A (CoA), 3-methylcrotonyl-CoA, and p.
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